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1

Ethanol self-administration and nicotine treatment induce brain levels of CYP2B6 and CYP2E1 in African green monkeys

Ferguson, Charmaine S., Miksys, Sharon, Palmour, Roberta M., Tyndale, Rachel F.

Journal:

Neuropharmacology

Year:

2013

Language:

english

File:

PDF, 2.13 MB

english, 2013

2

Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment

Sharon Miksys, Ewa Hoffmann, Rachel F Tyndale

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 795 KB

english, 2000

3

Regional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics

Sharon Miksys, Yushu Rao, Ewa Hoffmann, Deborah C. Mash, Rachel F. Tyndale

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 372 KB

english, 2002

4

Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics

Lisa A Howard, Sharon Miksys, Ewa Hoffmann, Deborah Mash, Rachel F Tyndale

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 341 KB

english, 2003

5

Phenobarbital increases monkey in vivo nicotine disposition and induces liver and brain CYP2B6 protein

Anna M Lee, Sharon Miksys, Rachel F Tyndale

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 271 KB

english, 2006

6

Immunogold labelling of serotonin-like and FMRFamide-like immunoreactive material in neurohaemal areas on abdominal nerves ofRhodnius prolixus

Sharon Miksys, Ian Orchard

Journal:

Cell and Tissue Research

Year:

1994

Language:

english

File:

PDF, 3.50 MB

english, 1994

7

Rat brain CYP2B induction by nicotine is persistent and does not involve nicotinic acetylcholine receptors

Jibran Y. Khokhar, Sharon L. Miksys, Rachel F. Tyndale

Journal:

Year:

2010

Language:

english

File:

PDF, 783 KB

english, 2010

8

Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake

Jiang Yue, Jibran Khokhar, Sharon Miksys, Rachel F. Tyndale

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 624 KB

english, 2009

9

The neuroprotective enzyme CYP2D6 increases in the brain with age and is lower in Parkinson's disease patients

Amandeep Mann, Sharon L. Miksys, Andrea Gaedigk, Stephen J. Kish, Deborah C. Mash, Rachel F. Tyndale

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 3.18 MB

english, 2012

10

CYP2B6 is expressed in African Green monkey brain and is induced by chronic nicotine treatment

Anna M. Lee, Sharon Miksys, Roberta Palmour, Rachel F. Tyndale

Journal:

Neuropharmacology

Year:

2006

Language:

english

File:

PDF, 1.15 MB

english, 2006

11

Induction of the drug metabolizing enzyme CYP2D in monkey brain by chronic nicotine treatment

Amandeep Mann, Sharon Miksys, Anna Lee, Deborah C. Mash, Rachel F. Tyndale

Journal:

Neuropharmacology

Year:

2008

Language:

english

File:

PDF, 2.15 MB

english, 2008

12

Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain

Sharon Miksys, Caryn Lerman, Peter G. Shields, Deborah C. Mash, Rachel F. Tyndale

Journal:

Neuropharmacology

Year:

2003

Language:

english

File:

PDF, 1.53 MB

english, 2003

13

Localization and Neurohemal Release of FMRFamide-Related Peptides in the Stick Insect Carausius morosus

Sharon Miksys, Angela B Lange, Ian Orchard, Victor Wong

Journal:

Year:

1997

Language:

english

File:

PDF, 1.30 MB

english, 1997

14

Potential role of CYP2D6 in the central nervous system

Cheng, Jie, Zhen, Yueying, Miksys, Sharon, Beyoğlu, Diren, Krausz, Kristopher W., Tyndale, Rachel F., Yu, Aiming, Idle, Jeffrey R., Gonzalez, Frank J.

Journal:

Year:

2013

Language:

english

File:

PDF, 557 KB

english, 2013

15

Rational design of novel CYP2A6 inhibitors

Raunio, Hannu, Tani, Niina, Juvonen, Risto, Fashe, Muluneh, Leppänen, Jukka, Zhao, Bin, Miksys, Sharon, Tyndale, Rachel, Rahnasto-Rilla, Minna

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 83 KB

english, 2013

16

Brain Drug-Metabolizing Cytochrome P450 Enzymes are Active In Vivo, Demonstrated by Mechanism-Based Enzyme Inhibition

Miksys, Sharon, Tyndale, Rachel F

Journal:

Neuropsychopharmacology

Year:

2009

Language:

english

File:

PDF, 147 KB

english, 2009

17

The Unique Regulation of Brain Cytochrome P450 2 (CYP2) Family Enzymes by Drugs and Genetics

Miksys, Sharon, Tyndale, Rachel F.

Journal:

Drug Metabolism Reviews

Year:

2004

Language:

english

File:

PDF, 715 KB

english, 2004

18

Effect of Brain CYP2B Inhibition on Brain Nicotine Levels and Nicotine Self-Administration

Garcia, Kristine L P, Coen, Kathy, Miksys, Sharon, Lê, Anh Dzung, Tyndale, Rachel F

Journal:

Neuropsychopharmacology

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

19

Cytochrome P450–mediated drug metabolism in the brain

Miksys, Sharon, Tyndale, Rachel

Journal:

Journal of Psychiatry and Neuroscience

Year:

2013

Language:

english

File:

PDF, 731 KB

english, 2013

20

The not-so-silent world: Measuring Arctic, Equatorial, and Antarctic soundscapes in the Atlantic Ocean

Haver, Samara M., Klinck, Holger, Nieukirk, Sharon L., Matsumoto, Haru, Dziak, Robert P., Miksis-Olds, Jennifer L.

Journal:

Deep Sea Research Part I: Oceanographic Research Papers

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

21

Rat brain CYP2D enzymatic metabolism alters acute and chronic haloperidol side-effects by different mechanisms

Miksys, Sharon, Wadji, Fariba Baghai, Tolledo, Edgor Cole, Remington, Gary, Nobrega, Jose N., Tyndale, Rachel F.

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

22

Rat brain CYP2D activity alters in vivo central oxycodone metabolism, levels and resulting analgesia

McMillan, Douglas M., Miksys, Sharon, Tyndale, Rachel F.

Journal:

Addiction Biology

Year:

2017

Language:

english

File:

PDF, 729 KB

english, 2017

23

Developmental Hippocampal Neuroplasticity in a Model of Nicotine Replacement Therapy during Pregnancy and Breastfeeding

Mahar, Ian, Bagot, Rosemary C., Davoli, Maria Antonietta, Miksys, Sharon, Tyndale, Rachel F., Walker, Claire-Dominique, Maheu, Marissa, Huang, Sheng-Hai, Wong, Tak Pan, Mechawar, Naguib, Homberg, Judi

Journal:

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

24

Making Silianted Slides For Mounting Sections

Journal:

Microscopy Today

Year:

1999

Language:

english

File:

PDF, 2.12 MB

english, 1999

25

A mouse model for investigating human brain CYP2D6

Tolledo, Edgor Cole, Stocco, Marlaina, Miksys, Sharon, Gonzales, Frank, Wadji, Fariba B., Zhao, Bin, Tyndale, Rachel F.

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2019

File:

PDF, 122 KB

2019

26

Propranolol is a mechanism‐based inhibitor of CYP2D and CYP2D6 in humanized CYP2D6‐transgenic mice: effects on activity and drug response

Tolledo, Edgor Cole, Miksys, Sharon, Gonzalez, Frank J., Tyndale, Rachel F.

Journal:

British Journal of Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.42 MB

english, 2019

27

Sex difference in dopamine D1-D2 receptor complex expression and signaling affects depression- and anxiety-like behaviors

Hasbi, Ahmed, Nguyen, Tuan, Rahal, Haneen, Manduca, Joshua D., Miksys, Sharon, Tyndale, Rachel F., Madras, Bertha K., Perreault, Melissa L., George, Susan R.

Journal:

Biology of Sex Differences

Year:

2020

Language:

english

File:

PDF, 2.35 MB

english, 2020

28

Human CYP2D6 Is Functional in Brain In Vivo: Evidence from Humanized CYP2D6 Transgenic Mice

Tolledo, Cole, Stocco, Marlaina R., Miksys, Sharon, Gonzalez, Frank J., Tyndale, Rachel F.

Journal:

Molecular Neurobiology

Year:

2020

Language:

english

File:

PDF, 1.31 MB

english, 2020

29

Human CYP2D6 in the Brain Is Protective Against Harmine-Induced Neurotoxicity: Evidence from Humanized CYP2D6 Transgenic Mice

Stocco, Marlaina R., Tolledo, Cole, Wadji, Fariba Baghai, Gonzalez, Frank J., Miksys, Sharon, Tyndale, Rachel F.

Journal:

Molecular Neurobiology

Year:

2020

File:

PDF, 1.86 MB

2020

30

The influence of tobacco smoke/nicotine on CYP2A expression in Human and African Green Monkey Lungs

Gao, Yuan, Miksys, Sharon, Palmour, Roberta M, Tyndale, Rachel F.

Journal:

Molecular Pharmacology

Year:

2020

File:

PDF, 1.28 MB

2020

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